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3D Bioplotter Research Papers
Displaying all papers by X. Nie (1 results)
A smart scaffold composed of three-dimensional printing and electrospinning techniques and its application in rat abdominal wall defects
Stem Cell Research & Therapy
2020
Volume 11, Article number 533
Background Biological composite scaffolds are increasingly being used in abdominal wall reconstruction but still have certain shortcomings. The present study describes here a novel three-dimensional (3D) scaffold fabricated by combining 3D printing (3DP) and electrospinning (ESP). Methods Biological composite scaffolds are composed of integrated 3DP interconnected macrofiber and random ESP microfiber networks. The 3DP scaffold retains intact 3D architecture and mechanical properties, while the ESP network serves as a cell entrapment system at the extracellular matrix (ECM) scale. Biological composite scaffolds are implanted in a defective rat abdominal wall to detect if it could induce early vascularization and reconstruction of…